Physiological Relevant
Scalable & High-Throughput
Translational Relevance
Cost-Effective
Regulatory Potential
Redefining Heart Drug Discovery
Pioneering innovation in drug discovery
At Endomimetics, we are pioneering the future of cardiovascular drug discovery. Our team brings together world-class expertise in biomedical engineering, clinical cardiology, and translational research to address one of medicine’s greatest challenges: atherosclerosis.
We have developed the proprietary 3D AtheroVascu Sheet Models—the first scalable, physiologically accurate in vitro models that replicate the progressive stages of atherosclerosis. Built on a cutting-edge ECM-mimicking nanomatrix, our platform empowers pharmaceutical, biotech, and academic partners to accelerate drug development, reduce costs, and improve the success rate of therapies targeting cardiovascular disease.
Stage-Specific Disease Modeling
We offer a suite of models that mirror the entire early atherogenesis process—from healthy arteries through endothelial dysfunction, monocyte adhesion, macrophage formation, foam cell development, and plaque formation. This enables precise, stage-specific drug testing and mechanistic studies.
Robust and Reproducible Data
Standardized protocols ensure consistent, reliable results that meet the rigorous demands of academic, industry, and regulatory partners. This reproducibility is crucial for preclinical validation and regulatory submissions.
Comprehensive Support and Collaboration
We provide not just models, but also contract research services, data analysis, and strategic partnership opportunities to integrate our technology into diverse research and development pipelines.
Stage-Specific Models
Stage-Leading Results
Blood tests
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Diagnostic imaging
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Virus tests
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Wellness screening
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